G883-0638 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-2,6-difluorobenzamide

G883-0638 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-2,6-difluorobenzamide
G883-0638 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-2,6-difluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0638
N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-2,6-difluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0638

Molecular Formula

C23H18F2N2O2 (C23 H18 F2 N2 O2)

Compound Name

N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-2,6-difluorobenzamide

IUPAC name

N-[(1-benzoyl-23-dihydro-1H-indol-5-yl)methyl]-26-difluorobenzamide

SMILES

O=C(c(c(F)ccc1)c1F)NCc(cc1)cc(CC2)c1N2C(c1ccccc1)=O

InChI

InChI=1S/C23H18F2N2O2/c24-18-7-4-8-19(25)21(18)22(28)26-14-15-9-10-20-17(13-15)11-12-27(20)23(29)16-5-2-1-3-6-16/h1-10,13H,11-12,14H2,(H,26,28)

InChI Key

JAJGTEMFMIZOEZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165460

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.741

Distribution Coefficient, logD

3.741

Water Solubility, LogSw

-4.33

Polar Surface Area

40.331

Acid Dissociation Constant (pKa)

10.69

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

G883-0638 in Drug Discovery

Included in Screening Libraries

Nucleic Acid Ligands (8311 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0638 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0638?
Check Price and Availability of G883-0638, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0638 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0638
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0638
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0638 available by request