G883-1043 Screening compound: 3-chloro-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide

G883-1043 Screening compound: 3-chloro-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide
G883-1043 Screening compound: 3-chloro-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-1043
3-chloro-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-1043

Molecular Formula

C22H18ClN3O2 (C22 H18 ClN3 O2)

Compound Name

3-chloro-N-{[1-(pyridine-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide

IUPAC name

3-chloro-N-{[1-(pyridine-4-carbonyl)-23-dihydro-1H-indol-5-yl]methyl}benzamide

SMILES

O=C(c1cccc(Cl)c1)NCc(cc1)cc(CC2)c1N2C(c1ccncc1)=O

InChI

InChI=1S/C22H18ClN3O2/c23-19-3-1-2-18(13-19)21(27)25-14-15-4-5-20-17(12-15)8-11-26(20)22(28)16-6-9-24-10-7-16/h1-7,9-10,12-13H,8,11,14H2,(H,25,27)

InChI Key

VHTILQGOXMNXMD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165598

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.86

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.092

Distribution Coefficient, logD

3.092

Water Solubility, LogSw

-3.64

Polar Surface Area

49.759

Acid Dissociation Constant (pKa)

11.67

Base Dissociation Constant (pKb)

3.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

G883-1043 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Nucleic Acid Ligands (8311 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-1043 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-1043?
Check Price and Availability of G883-1043, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-1043 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-1043
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-1043
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-1043 available by request