G883-1622 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide

G883-1622 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide
G883-1622 Screening compound: N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-1622
N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-1622

Molecular Formula

C32H33N3O2 (C32 H33 N3 O2)

Compound Name

N-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide

IUPAC name

N-{[1-(3-methylbenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-3-(2349-tetrahydro-1H-carbazol-9-yl)propanamide

SMILES

Cc1cccc(C(N(CC2)c3c2cc(CNC(CCn2c(cccc4)c4c4c2CCCC4)=O)cc3)=O)c1

InChI

InChI=1S/C32H33N3O2/c1-22-7-6-8-25(19-22)32(37)35-17-15-24-20-23(13-14-28(24)35)21-33-31(36)16-18-34-29-11-4-2-9-26(29)27-10-3-5-12-30(27)34/h2,4,6-9,11,13-14,19-20H,3,5,10,12,15-18,21H2,1H3,(H,33,36)

InChI Key

OQPQXYBLRXBWSX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165703

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.63

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.578

Distribution Coefficient, logD

5.578

Water Solubility, LogSw

-5.60

Polar Surface Area

41.473

Acid Dissociation Constant (pKa)

13.40

Base Dissociation Constant (pKb)

0.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.30

G883-1622 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

MCL1 Targeted Library (12200 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-1622 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-1622?
Check Price and Availability of G883-1622, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-1622 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-1622
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-1622
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-1622 available by request