G884-1516 Screening compound: 2-{2,3-dioxo-4-[(pyridin-4-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}-N-[2-(2-methylphenyl)ethyl]acetamide

G884-1516 Screening compound: 2-{2,3-dioxo-4-[(pyridin-4-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}-N-[2-(2-methylphenyl)ethyl]acetamide
G884-1516 Screening compound: 2-{2,3-dioxo-4-[(pyridin-4-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}-N-[2-(2-methylphenyl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G884-1516
2-{2,3-dioxo-4-[(pyridin-4-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}-N-[2-(2-methylphenyl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G884-1516

Molecular Formula

C24H23N5O3 (C24 H23 N5 O3)

Compound Name

2-{2,3-dioxo-4-[(pyridin-4-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-1-yl}-N-[2-(2-methylphenyl)ethyl]acetamide

IUPAC name

2-{23-dioxo-4-[(pyridin-4-yl)methyl]-1H2H3H4H-pyrido[23-b]pyrazin-1-yl}-N-[2-(2-methylphenyl)ethyl]acetamide

SMILES

Cc1c(CCNC(CN(c2cccnc2N(Cc2ccncc2)C2=O)C2=O)=O)cccc1

InChI

InChI=1S/C24H23N5O3/c1-17-5-2-3-6-19(17)10-14-26-21(30)16-28-20-7-4-11-27-22(20)29(24(32)23(28)31)15-18-8-12-25-13-9-18/h2-9,11-13H,10,14-16H2,1H3,(H,26,30)

InChI Key

FPHOXUQJTPXZLE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27166055

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.886

Distribution Coefficient, logD

1.885

Water Solubility, LogSw

-2.11

Polar Surface Area

74.595

Acid Dissociation Constant (pKa)

14.61

Base Dissociation Constant (pKb)

4.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

G884-1516 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G884-1516 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G884-1516?
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What is the minimum amount of G884-1516 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G884-1516
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G884-1516
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G884-1516 available by request