G896-0342 Screening compound: 6-[4-(4-chlorophenyl)piperazine-1-carbonyl]-3-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

G896-0342 Screening compound: 6-[4-(4-chlorophenyl)piperazine-1-carbonyl]-3-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
G896-0342 Screening compound: 6-[4-(4-chlorophenyl)piperazine-1-carbonyl]-3-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G896-0342
6-[4-(4-chlorophenyl)piperazine-1-carbonyl]-3-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G896-0342

Molecular Formula

C18H17ClN4O2S (C18 H17 ClN4 O2 S)

Compound Name

6-[4-(4-chlorophenyl)piperazine-1-carbonyl]-3-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

IUPAC name

6-[4-(4-chlorophenyl)piperazine-1-carbonyl]-3-methyl-5H-[13]thiazolo[32-a]pyrimidin-5-one

SMILES

CC(N12)=CSC2=NC=C(C(N(CC2)CCN2c(cc2)ccc2Cl)=O)C1=O

InChI

InChI=1S/C18H17ClN4O2S/c1-12-11-26-18-20-10-15(17(25)23(12)18)16(24)22-8-6-21(7-9-22)14-4-2-13(19)3-5-14/h2-5,10-11H,6-9H2,1H3

InChI Key

KNVHTTATVHQYKG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27167187

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.88

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.262

Distribution Coefficient, logD

2.262

Water Solubility, LogSw

-2.86

Polar Surface Area

45.016

Acid Dissociation Constant (pKa)

28.16

Base Dissociation Constant (pKb)

5.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G896-0342 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G896-0342 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G896-0342?
Check Price and Availability of G896-0342, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G896-0342 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G896-0342
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G896-0342
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G896-0342 available by request