G905-0717 Screening compound: 9-methyl-3-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]-4H-pyrido[1,2-a]pyrimidin-4-one

G905-0717 Screening compound: 9-methyl-3-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]-4H-pyrido[1,2-a]pyrimidin-4-one
G905-0717 Screening compound: 9-methyl-3-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]-4H-pyrido[1,2-a]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G905-0717
9-methyl-3-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]-4H-pyrido[1,2-a]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G905-0717

Molecular Formula

C18H18N6O2 (C18 H18 N6 O2)

Compound Name

9-methyl-3-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]-4H-pyrido[1,2-a]pyrimidin-4-one

IUPAC name

9-methyl-3-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]-4H-pyrido[12-a]pyrimidin-4-one

SMILES

CC(C1=NC=C2C(N(CC3)CCN3c3ncccn3)=O)=CC=CN1C2=O

InChI

InChI=1S/C18H18N6O2/c1-13-4-2-7-24-15(13)21-12-14(17(24)26)16(25)22-8-10-23(11-9-22)18-19-5-3-6-20-18/h2-7,12H,8-11H2,1H3

InChI Key

XZYSILBNSXZTFT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15074774

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.38

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.926

Distribution Coefficient, logD

0.926

Water Solubility, LogSw

-0.91

Polar Surface Area

62.765

Acid Dissociation Constant (pKa)

21.15

Base Dissociation Constant (pKb)

2.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G905-0717 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G905-0717 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G905-0717?
Check Price and Availability of G905-0717, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G905-0717 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G905-0717
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G905-0717
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G905-0717 available by request