G937-1748 Screening compound: ethyl 4-[(3-{[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]carbamoyl}piperidin-1-yl)sulfonyl]-1,2,5-trimethyl-1H-pyrrole-3-carboxylate

G937-1748 Screening compound: ethyl 4-[(3-{[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]carbamoyl}piperidin-1-yl)sulfonyl]-1,2,5-trimethyl-1H-pyrrole-3-carboxylate
G937-1748 Screening compound: ethyl 4-[(3-{[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]carbamoyl}piperidin-1-yl)sulfonyl]-1,2,5-trimethyl-1H-pyrrole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G937-1748
ethyl 4-[(3-{[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]carbamoyl}piperidin-1-yl)sulfonyl]-1,2,5-trimethyl-1H-pyrrole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G937-1748

Molecular Formula

C20H29N5O5S3 (C20 H29 N5 O5 S3)

Compound Name

ethyl 4-[(3-{[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]carbamoyl}piperidin-1-yl)sulfonyl]-1,2,5-trimethyl-1H-pyrrole-3-carboxylate

IUPAC name

ethyl 4-[(3-{[5-(ethylsulfanyl)-134-thiadiazol-2-yl]carbamoyl}piperidin-1-yl)sulfonyl]-125-trimethyl-1H-pyrrole-3-carboxylate

SMILES

CCOC(c1c(C)n(C)c(C)c1S(N(CCC1)CC1C(Nc1nnc(SCC)s1)=O)(=O)=O)=O

InChI

InChI=1S/C20H29N5O5S3/c1-6-30-18(27)15-12(3)24(5)13(4)16(15)33(28,29)25-10-8-9-14(11-25)17(26)21-19-22-23-20(32-19)31-7-2/h14H,6-11H2,1-5H3,(H,21,22,26)/t14-/m0/s1

InChI Key

KFWVOWKHTKSJPS-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD15076130

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

515.68

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.387

Distribution Coefficient, logD

2.340

Water Solubility, LogSw

-2.72

Polar Surface Area

101.413

Acid Dissociation Constant (pKa)

8.35

Base Dissociation Constant (pKb)

0.64

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

60.00

G937-1748 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Others
  • GPCR
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G937-1748 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G937-1748?
Check Price and Availability of G937-1748, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G937-1748 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G937-1748
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G937-1748
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G937-1748 available by request