H025-0252B Screening compound: 8-fluoro-2-methyl-5-[2-(3-pyridyl)-1-ethynyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

H025-0252B Screening compound: 8-fluoro-2-methyl-5-[2-(3-pyridyl)-1-ethynyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
H025-0252B Screening compound: 8-fluoro-2-methyl-5-[2-(3-pyridyl)-1-ethynyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole alternative view

Chemical Structure Depiction of ChemDiv screening compound H025-0252B
8-fluoro-2-methyl-5-[2-(3-pyridyl)-1-ethynyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

H025-0252B

Molecular Formula

C19H16FN3 (C19 H16 FN3)

Compound Name

8-fluoro-2-methyl-5-[2-(3-pyridyl)-1-ethynyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

IUPAC name

n/a

SMILES

CN(CC1)Cc(c2c3ccc(F)c2)c1n3C#Cc1cnccc1

InChI

InChI=1S/C19H16FN3/c1-22-9-7-19-17(13-22)16-11-15(20)4-5-18(16)23(19)10-6-14-3-2-8-21-12-14/h2-5,8,11-12H,7,9,13H2,1H3

InChI Key

DPTCIIYSUBFZKY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27214531

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

305.35

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

2.880

Distribution Coefficient, logD

2.767

Water Solubility, LogSw

-2.80

Polar Surface Area

14.109

Acid Dissociation Constant (pKa)

28.19

Base Dissociation Constant (pKb)

6.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

H025-0252B in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with H025-0252B chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound H025-0252B?
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What is the minimum amount of H025-0252B you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for H025-0252B
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for H025-0252B
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of H025-0252B available by request