H025-0443C Screening compound: 1-[5-(3-fluorobenzenesulfonyl)pyridine-2-carbonyl]piperazine

H025-0443C Screening compound: 1-[5-(3-fluorobenzenesulfonyl)pyridine-2-carbonyl]piperazine
H025-0443C Screening compound: 1-[5-(3-fluorobenzenesulfonyl)pyridine-2-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound H025-0443C
1-[5-(3-fluorobenzenesulfonyl)pyridine-2-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

H025-0443C

Molecular Formula

C16H16FN3O3S (C16 H16 FN3 O3 S)

Compound Name

1-[5-(3-fluorobenzenesulfonyl)pyridine-2-carbonyl]piperazine

IUPAC name

1-[5-(3-fluorobenzenesulfonyl)pyridine-2-carbonyl]piperazine

SMILES

O=C(c(cc1)ncc1S(c1cc(F)ccc1)(=O)=O)N1CCNCC1

InChI

InChI=1S/C16H16FN3O3S/c17-12-2-1-3-13(10-12)24(22,23)14-4-5-15(19-11-14)16(21)20-8-6-18-7-9-20/h1-5,10-11,18H,6-9H2

InChI Key

TWSLDFKIANICAL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27214615

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

349.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.856

Distribution Coefficient, logD

0.293

Water Solubility, LogSw

-2.40

Polar Surface Area

67.486

Acid Dissociation Constant (pKa)

26.95

Base Dissociation Constant (pKb)

7.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

H025-0443C in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

KRAS-Targeted Library (16000 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with H025-0443C chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound H025-0443C?
Check Price and Availability of H025-0443C, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of H025-0443C you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for H025-0443C
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for H025-0443C
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of H025-0443C available by request