H027-4241 Screening compound: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione

H027-4241 Screening compound: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione
H027-4241 Screening compound: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione alternative view

Chemical Structure Depiction of ChemDiv screening compound H027-4241
1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

H027-4241

Molecular Formula

C10H13FN2O5 (C10 H13 FN2 O5)

Compound Name

1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione

IUPAC name

1-[(2R3R4R5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1234-tetrahydropyrimidine-24-dione

SMILES

C[C@@]1([C@H](N(C=CC(N2)=O)C2=O)O[C@H](CO)[C@H]1O)F

InChI

InChI=1S/C10H13FN2O5/c1-10(11)7(16)5(4-14)18-8(10)13-3-2-6(15)12-9(13)17/h2-3,5,7-8,14,16H,4H2,1H3,(H,12,15,17)/t5-,7+,8+,10+/m0/s1

InChI Key

ARKKGZQTGXJVKW-LJHRJBCISA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

260.22

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

-0.938

Distribution Coefficient, logD

-0.938

Water Solubility, LogSw

-0.84

Polar Surface Area

81.510

Acid Dissociation Constant (pKa)

10.21

Base Dissociation Constant (pKb)

-3.44

Number of Chiral Centers

4.00

Percent sp3 carbon bonding

60.00

H027-4241 in Drug Discovery

Included in Screening Libraries

STING Agonist Library (5895 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with H027-4241 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound H027-4241?
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What is the minimum amount of H027-4241 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for H027-4241
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for H027-4241
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of H027-4241 available by request