J015-0234 Screening compound: 3-bromo-N-[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]-6-(4H-1,2,4-triazol-4-yl)pyridine-2-carboxamide

J015-0234 Screening compound: 3-bromo-N-[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]-6-(4H-1,2,4-triazol-4-yl)pyridine-2-carboxamide
J015-0234 Screening compound: 3-bromo-N-[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]-6-(4H-1,2,4-triazol-4-yl)pyridine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J015-0234
3-bromo-N-[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]-6-(4H-1,2,4-triazol-4-yl)pyridine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J015-0234

Molecular Formula

C19H16BrF3N6O2 (C19 H16 BrF3 N6 O2)

Compound Name

3-bromo-N-[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]-6-(4H-1,2,4-triazol-4-yl)pyridine-2-carboxamide

IUPAC name

3-bromo-N-[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]-6-(4H-124-triazol-4-yl)pyridine-2-carboxamide

SMILES

O=C(c(nc(cc1)-n2cnnc2)c1Br)Nc(cc(C(F)(F)F)cc1)c1N1CCOCC1

InChI

InChI=1S/C19H16BrF3N6O2/c20-13-2-4-16(29-10-24-25-11-29)27-17(13)18(30)26-14-9-12(19(21,22)23)1-3-15(14)28-5-7-31-8-6-28/h1-4,9-11H,5-8H2,(H,26,30)

InChI Key

IHMWTWGIQSEICU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15078233

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.27

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.758

Distribution Coefficient, logD

1.355

Water Solubility, LogSw

-4.25

Polar Surface Area

68.573

Acid Dissociation Constant (pKa)

5.00

Base Dissociation Constant (pKb)

1.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

J015-0234 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with J015-0234 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J015-0234?
Check Price and Availability of J015-0234, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J015-0234 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J015-0234
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J015-0234
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J015-0234 available by request