J025-1133 Screening compound: 3-(2-fluorophenyl)-7-(naphthalen-1-yl)-4H,5H,6H,7H-thieno[3,2-b]pyridin-5-one

J025-1133 Screening compound: 3-(2-fluorophenyl)-7-(naphthalen-1-yl)-4H,5H,6H,7H-thieno[3,2-b]pyridin-5-one
J025-1133 Screening compound: 3-(2-fluorophenyl)-7-(naphthalen-1-yl)-4H,5H,6H,7H-thieno[3,2-b]pyridin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound J025-1133
3-(2-fluorophenyl)-7-(naphthalen-1-yl)-4H,5H,6H,7H-thieno[3,2-b]pyridin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J025-1133

Molecular Formula

C23H16FNOS (C23 H16 FNOS)

Compound Name

3-(2-fluorophenyl)-7-(naphthalen-1-yl)-4H,5H,6H,7H-thieno[3,2-b]pyridin-5-one

IUPAC name

3-(2-fluorophenyl)-7-(naphthalen-1-yl)-4H5H6H7H-thieno[32-b]pyridin-5-one

SMILES

O=C(CC1c2cccc3ccccc23)Nc2c1scc2-c(cccc1)c1F

InChI

InChI=1S/C23H16FNOS/c24-20-11-4-3-9-17(20)19-13-27-23-18(12-21(26)25-22(19)23)16-10-5-7-14-6-1-2-8-15(14)16/h1-11,13,18H,12H2,(H,25,26)/t18-/m1/s1

InChI Key

SUHRWFYSPUPOMA-GOSISDBHSA-N

MDL Number (MFCD)

MFCD27219495

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.45

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

5.173

Distribution Coefficient, logD

5.173

Water Solubility, LogSw

-6.30

Polar Surface Area

23.011

Acid Dissociation Constant (pKa)

12.23

Base Dissociation Constant (pKb)

-5.24

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

8.70

J025-1133 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with J025-1133 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J025-1133?
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What is the minimum amount of J025-1133 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J025-1133
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J025-1133
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J025-1133 available by request