J026-4325 Screening compound: methyl 4-{[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]methyl}benzoate

J026-4325 Screening compound: methyl 4-{[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]methyl}benzoate
J026-4325 Screening compound: methyl 4-{[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]methyl}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-4325
methyl 4-{[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]methyl}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-4325

Molecular Formula

C24H26N4O5 (C24 H26 N4 O5)

Compound Name

methyl 4-{[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]methyl}benzoate

IUPAC name

methyl 4-{[17-dimethyl-24-dioxo-5-(piperidine-1-carbonyl)-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl]methyl}benzoate

SMILES

Cc(cc1C(N2CCCCC2)=O)nc(N(C)C(N2Cc(cc3)ccc3C(OC)=O)=O)c1C2=O

InChI

InChI=1S/C24H26N4O5/c1-15-13-18(21(29)27-11-5-4-6-12-27)19-20(25-15)26(2)24(32)28(22(19)30)14-16-7-9-17(10-8-16)23(31)33-3/h7-10,13H,4-6,11-12,14H2,1-3H3

InChI Key

IEONXURZTLCHIF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27219951

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.49

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.178

Distribution Coefficient, logD

3.178

Water Solubility, LogSw

-3.22

Polar Surface Area

78.831

Acid Dissociation Constant (pKa)

26.88

Base Dissociation Constant (pKb)

3.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

J026-4325 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with J026-4325 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-4325?
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What is the minimum amount of J026-4325 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-4325
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-4325
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-4325 available by request