J077-1251 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[3-(morpholine-4-carbonyl)phenyl]-1,3-diazinan-2-one

J077-1251 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[3-(morpholine-4-carbonyl)phenyl]-1,3-diazinan-2-one
J077-1251 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[3-(morpholine-4-carbonyl)phenyl]-1,3-diazinan-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound J077-1251
1-[(4-fluorophenyl)methyl]-3-[3-(morpholine-4-carbonyl)phenyl]-1,3-diazinan-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J077-1251

Molecular Formula

C22H24FN3O3 (C22 H24 FN3 O3)

Compound Name

1-[(4-fluorophenyl)methyl]-3-[3-(morpholine-4-carbonyl)phenyl]-1,3-diazinan-2-one

IUPAC name

1-[(4-fluorophenyl)methyl]-3-[3-(morpholine-4-carbonyl)phenyl]-13-diazinan-2-one

SMILES

O=C(c1cccc(N(CCCN2Cc(cc3)ccc3F)C2=O)c1)N1CCOCC1

InChI

InChI=1S/C22H24FN3O3/c23-19-7-5-17(6-8-19)16-25-9-2-10-26(22(25)28)20-4-1-3-18(15-20)21(27)24-11-13-29-14-12-24/h1,3-8,15H,2,9-14,16H2

InChI Key

TUUYQDSCICWIRV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14856797

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.204

Distribution Coefficient, logD

2.204

Water Solubility, LogSw

-2.51

Polar Surface Area

44.354

Acid Dissociation Constant (pKa)

27.49

Base Dissociation Constant (pKb)

-1.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

J077-1251 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with J077-1251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J077-1251?
Check Price and Availability of J077-1251, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J077-1251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J077-1251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J077-1251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J077-1251 available by request