K061-0088 Screening compound: 1-(4-fluorophenyl)-4-[5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine

K061-0088 Screening compound: 1-(4-fluorophenyl)-4-[5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine
K061-0088 Screening compound: 1-(4-fluorophenyl)-4-[5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound K061-0088
1-(4-fluorophenyl)-4-[5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K061-0088

Molecular Formula

C22H17F4N5OS (C22 H17 F4 N5 OS)

Compound Name

1-(4-fluorophenyl)-4-[5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine

IUPAC name

1-(4-fluorophenyl)-4-[5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carbonyl]piperazine

SMILES

O=C(c1nn2c(C(F)(F)F)cc(-c3cccs3)nc2c1)N(CC1)CCN1c(cc1)ccc1F

InChI

InChI=1S/C22H17F4N5OS/c23-14-3-5-15(6-4-14)29-7-9-30(10-8-29)21(32)17-13-20-27-16(18-2-1-11-33-18)12-19(22(24,25)26)31(20)28-17/h1-6,11-13H,7-10H2

InChI Key

RFKOCDXSTXVFMM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01077178

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.699

Distribution Coefficient, logD

4.699

Water Solubility, LogSw

-4.71

Polar Surface Area

39.325

Acid Dissociation Constant (pKa)

28.08

Base Dissociation Constant (pKb)

1.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

K061-0088 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-HIV1 Library (19540 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K061-0088 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K061-0088?
Check Price and Availability of K061-0088, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K061-0088 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K061-0088
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K061-0088
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K061-0088 available by request