K072-0191 Screening compound: 2-[(2E)-2-[(5-bromothiophen-2-yl)methylidene]hydrazin-1-yl]-5,7-dichloroquinolin-8-ol

K072-0191 Screening compound: 2-[(2E)-2-[(5-bromothiophen-2-yl)methylidene]hydrazin-1-yl]-5,7-dichloroquinolin-8-ol
K072-0191 Screening compound: 2-[(2E)-2-[(5-bromothiophen-2-yl)methylidene]hydrazin-1-yl]-5,7-dichloroquinolin-8-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound K072-0191
2-[(2E)-2-[(5-bromothiophen-2-yl)methylidene]hydrazin-1-yl]-5,7-dichloroquinolin-8-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K072-0191

Molecular Formula

C14H8BrCl2N3OS (C14 H8 BrCl2 N3 OS)

Compound Name

2-[(2E)-2-[(5-bromothiophen-2-yl)methylidene]hydrazin-1-yl]-5,7-dichloroquinolin-8-ol

IUPAC name

2-[(2E)-2-[(5-bromothiophen-2-yl)methylidene]hydrazin-1-yl]-57-dichloroquinolin-8-ol

SMILES

Oc(c(Cl)cc(Cl)c1cc2)c1nc2N/N=C/c(s1)ccc1Br

InChI

InChI=1S/C14H8BrCl2N3OS/c15-11-3-1-7(22-11)6-18-20-12-4-2-8-9(16)5-10(17)14(21)13(8)19-12/h1-6,21H,(H,19,20)

InChI Key

FIWDHVWOPGWCAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01248753

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.11

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.762

Distribution Coefficient, logD

6.505

Water Solubility, LogSw

-6.45

Polar Surface Area

47.541

Acid Dissociation Constant (pKa)

7.51

Base Dissociation Constant (pKb)

5.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

K072-0191 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with K072-0191 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K072-0191?
Check Price and Availability of K072-0191, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K072-0191 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K072-0191
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K072-0191
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K072-0191 available by request