K087-0185 Screening compound: N'-[(E)-{3-[(4-chloro-3,5-dimethylphenoxy)methyl]-4-methoxyphenyl}methylidene]-3-(1H-indol-3-yl)propanehydrazide

K087-0185 Screening compound: N'-[(E)-{3-[(4-chloro-3,5-dimethylphenoxy)methyl]-4-methoxyphenyl}methylidene]-3-(1H-indol-3-yl)propanehydrazide
K087-0185 Screening compound: N'-[(E)-{3-[(4-chloro-3,5-dimethylphenoxy)methyl]-4-methoxyphenyl}methylidene]-3-(1H-indol-3-yl)propanehydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound K087-0185
N'-[(E)-{3-[(4-chloro-3,5-dimethylphenoxy)methyl]-4-methoxyphenyl}methylidene]-3-(1H-indol-3-yl)propanehydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K087-0185

Molecular Formula

C28H28ClN3O3 (C28 H28 ClN3 O3)

Compound Name

N'-[(E)-{3-[(4-chloro-3,5-dimethylphenoxy)methyl]-4-methoxyphenyl}methylidene]-3-(1H-indol-3-yl)propanehydrazide

IUPAC name

N'-[(E)-{3-[(4-chloro-35-dimethylphenoxy)methyl]-4-methoxyphenyl}methylidene]-3-(1H-indol-3-yl)propanehydrazide

SMILES

Cc1cc(OCc(cc(/C=N/NC(CCc2c[nH]c3c2cccc3)=O)cc2)c2OC)cc(C)c1Cl

InChI

InChI=1S/C28H28ClN3O3/c1-18-12-23(13-19(2)28(18)29)35-17-22-14-20(8-10-26(22)34-3)15-31-32-27(33)11-9-21-16-30-25-7-5-4-6-24(21)25/h4-8,10,12-16,30H,9,11,17H2,1-3H3,(H,32,33)

InChI Key

ZHGDZPYOVZOKAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01539002

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.466

Distribution Coefficient, logD

6.466

Water Solubility, LogSw

-6.50

Polar Surface Area

60.070

Acid Dissociation Constant (pKa)

10.73

Base Dissociation Constant (pKb)

3.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.40

K087-0185 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

New Agro Library (44492 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Agro:
  • Agro
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with K087-0185 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K087-0185?
Check Price and Availability of K087-0185, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K087-0185 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K087-0185
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K087-0185
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K087-0185 available by request