K216-7973 Screening compound: 8-(2,3-diphenylquinoxaline-6-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane

K216-7973 Screening compound: 8-(2,3-diphenylquinoxaline-6-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane
K216-7973 Screening compound: 8-(2,3-diphenylquinoxaline-6-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound K216-7973
8-(2,3-diphenylquinoxaline-6-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K216-7973

Molecular Formula

C28H25N3O3 (C28 H25 N3 O3)

Compound Name

8-(2,3-diphenylquinoxaline-6-carbonyl)-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-(23-diphenylquinoxaline-6-carbonyl)-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c1cc2nc(-c3ccccc3)c(-c3ccccc3)nc2cc1)N(CC1)CCC11OCCO1

InChI

InChI=1S/C28H25N3O3/c32-27(31-15-13-28(14-16-31)33-17-18-34-28)22-11-12-23-24(19-22)30-26(21-9-5-2-6-10-21)25(29-23)20-7-3-1-4-8-20/h1-12,19H,13-18H2

InChI Key

NPVRAFRNEBMMEA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15081599

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.659

Distribution Coefficient, logD

3.659

Water Solubility, LogSw

-4.03

Polar Surface Area

49.254

Acid Dissociation Constant (pKa)

27.30

Base Dissociation Constant (pKb)

3.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

K216-7973 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K216-7973 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K216-7973?
Check Price and Availability of K216-7973, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K216-7973 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K216-7973
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K216-7973
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K216-7973 available by request