K216-8455 Screening compound: N-[2-(4-ethylpiperazin-1-yl)ethyl]-2,3-bis(3-methylphenyl)quinoxaline-6-carboxamide

K216-8455 Screening compound: N-[2-(4-ethylpiperazin-1-yl)ethyl]-2,3-bis(3-methylphenyl)quinoxaline-6-carboxamide
K216-8455 Screening compound: N-[2-(4-ethylpiperazin-1-yl)ethyl]-2,3-bis(3-methylphenyl)quinoxaline-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K216-8455
N-[2-(4-ethylpiperazin-1-yl)ethyl]-2,3-bis(3-methylphenyl)quinoxaline-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K216-8455

Molecular Formula

C31H35N5O (C31 H35 N5 O)

Compound Name

N-[2-(4-ethylpiperazin-1-yl)ethyl]-2,3-bis(3-methylphenyl)quinoxaline-6-carboxamide

IUPAC name

N-[2-(4-ethylpiperazin-1-yl)ethyl]-23-bis(3-methylphenyl)quinoxaline-6-carboxamide

SMILES

CCN1CCN(CCNC(c2cc3nc(-c4cc(C)ccc4)c(-c4cc(C)ccc4)nc3cc2)=O)CC1

InChI

InChI=1S/C31H35N5O/c1-4-35-15-17-36(18-16-35)14-13-32-31(37)26-11-12-27-28(21-26)34-30(25-10-6-8-23(3)20-25)29(33-27)24-9-5-7-22(2)19-24/h5-12,19-21H,4,13-18H2,1-3H3,(H,32,37)

InChI Key

NRRCXVFYARJXRE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15081684

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.65

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.721

Distribution Coefficient, logD

3.929

Water Solubility, LogSw

-4.33

Polar Surface Area

49.943

Acid Dissociation Constant (pKa)

12.38

Base Dissociation Constant (pKb)

8.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.30

K216-8455 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

CNS Targets (44014 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with K216-8455 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K216-8455?
Check Price and Availability of K216-8455, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K216-8455 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K216-8455
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K216-8455
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K216-8455 available by request