K250-0385 Screening compound: 6-[(4-nitrobenzyl)sulfanyl][1,3]benzimidazo[1,2-c]quinazoline

K250-0385 Screening compound: 6-[(4-nitrobenzyl)sulfanyl][1,3]benzimidazo[1,2-c]quinazoline
K250-0385 Screening compound: 6-[(4-nitrobenzyl)sulfanyl][1,3]benzimidazo[1,2-c]quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound K250-0385
6-[(4-nitrobenzyl)sulfanyl][1,3]benzimidazo[1,2-c]quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K250-0385

Molecular Formula

C21H14N4O2S (C21 H14 N4 O2 S)

Compound Name

6-[(4-nitrobenzyl)sulfanyl][1,3]benzimidazo[1,2-c]quinazoline

IUPAC name

9-{[(4-nitrophenyl)methyl]sulfanyl}-81017-triazatetracyclo[8.7.0.0^{27}.0^{1116}]heptadeca-1(17)246811(16)1214-octaene

SMILES

[O-][N+](c1ccc(CSc2nc(cccc3)c3c3nc(cccc4)c4n23)cc1)=O

InChI

InChI=1S/C21H14N4O2S/c26-25(27)15-11-9-14(10-12-15)13-28-21-23-17-6-2-1-5-16(17)20-22-18-7-3-4-8-19(18)24(20)21/h1-12H,13H2

InChI Key

XGLUMQPHFVLSLR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06507998

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.296

Distribution Coefficient, logD

5.294

Water Solubility, LogSw

-5.92

Polar Surface Area

50.200

Acid Dissociation Constant (pKa)

22.98

Base Dissociation Constant (pKb)

5.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

K250-0385 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K250-0385 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K250-0385?
Check Price and Availability of K250-0385, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K250-0385 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K250-0385
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K250-0385
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K250-0385 available by request