K259-0008 Screening compound: 3-(1,3-benzothiazol-2-yl)-6-tert-butyl-8-hydroxy-2H-chromen-2-one

K259-0008 Screening compound: 3-(1,3-benzothiazol-2-yl)-6-tert-butyl-8-hydroxy-2H-chromen-2-one
K259-0008 Screening compound: 3-(1,3-benzothiazol-2-yl)-6-tert-butyl-8-hydroxy-2H-chromen-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K259-0008
3-(1,3-benzothiazol-2-yl)-6-tert-butyl-8-hydroxy-2H-chromen-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K259-0008

Molecular Formula

C20H17NO3S (C20 H17 NO3 S)

Compound Name

3-(1,3-benzothiazol-2-yl)-6-tert-butyl-8-hydroxy-2H-chromen-2-one

IUPAC name

3-(13-benzothiazol-2-yl)-6-tert-butyl-8-hydroxy-2H-chromen-2-one

SMILES

CC(C)(C)c(cc1O)cc(C=C2c3nc(cccc4)c4s3)c1OC2=O

InChI

InChI=1S/C20H17NO3S/c1-20(2,3)12-8-11-9-13(19(23)24-17(11)15(22)10-12)18-21-14-6-4-5-7-16(14)25-18/h4-10,22H,1-3H3

InChI Key

BZGKMGFKYUXRKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15084133

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.444

Distribution Coefficient, logD

5.415

Water Solubility, LogSw

-5.27

Polar Surface Area

46.841

Acid Dissociation Constant (pKa)

8.57

Base Dissociation Constant (pKb)

-4.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

K259-0008 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with K259-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K259-0008?
Check Price and Availability of K259-0008, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K259-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K259-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K259-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K259-0008 available by request