K263-0649 Screening compound: 2-({3-[2-(dimethylamino)ethyl]-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl}sulfanyl)-N~1~-(2-methoxyphenyl)acetamide

K263-0649 Screening compound: 2-({3-[2-(dimethylamino)ethyl]-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl}sulfanyl)-N~1~-(2-methoxyphenyl)acetamide
K263-0649 Screening compound: 2-({3-[2-(dimethylamino)ethyl]-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl}sulfanyl)-N~1~-(2-methoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K263-0649
2-({3-[2-(dimethylamino)ethyl]-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl}sulfanyl)-N~1~-(2-methoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K263-0649

Molecular Formula

C23H24N4O3S2 (C23 H24 N4 O3 S2)

Compound Name

2-({3-[2-(dimethylamino)ethyl]-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl}sulfanyl)-N~1~-(2-methoxyphenyl)acetamide

IUPAC name

2-({5-[2-(dimethylamino)ethyl]-6-oxo-8-thia-35-diazatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)31012-pentaen-4-yl}sulfanyl)-N-(2-methoxyphenyl)acetamide

SMILES

CN(C)CCN(C1=O)C(SCC(Nc(cccc2)c2OC)=O)=Nc2c1sc1c2cccc1

InChI

InChI=1S/C23H24N4O3S2/c1-26(2)12-13-27-22(29)21-20(15-8-4-7-11-18(15)32-21)25-23(27)31-14-19(28)24-16-9-5-6-10-17(16)30-3/h4-11H,12-14H2,1-3H3,(H,24,28)

InChI Key

ATKGSJHPCUFRCD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15085581

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

468.6

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.597

Distribution Coefficient, logD

1.827

Water Solubility, LogSw

-3.87

Polar Surface Area

58.463

Acid Dissociation Constant (pKa)

11.57

Base Dissociation Constant (pKb)

9.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

K263-0649 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

CNS Targets (44014 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Targeted Diversity Library (40567 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Nervous system

References: we are preparing a list of scientific research reports with K263-0649 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K263-0649?
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What is the minimum amount of K263-0649 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K263-0649
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K263-0649
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K263-0649 available by request