K264-0095 Screening compound: 4-amino-5-(4-fluorobenzoyl)-N-(3-methylphenyl)-2-[(2-methylphenyl)amino]thiophene-3-carboxamide

K264-0095 Screening compound: 4-amino-5-(4-fluorobenzoyl)-N-(3-methylphenyl)-2-[(2-methylphenyl)amino]thiophene-3-carboxamide
K264-0095 Screening compound: 4-amino-5-(4-fluorobenzoyl)-N-(3-methylphenyl)-2-[(2-methylphenyl)amino]thiophene-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K264-0095
4-amino-5-(4-fluorobenzoyl)-N-(3-methylphenyl)-2-[(2-methylphenyl)amino]thiophene-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K264-0095

Molecular Formula

C26H22FN3O2S (C26 H22 FN3 O2 S)

Compound Name

4-amino-5-(4-fluorobenzoyl)-N-(3-methylphenyl)-2-[(2-methylphenyl)amino]thiophene-3-carboxamide

IUPAC name

4-amino-5-(4-fluorobenzoyl)-N-(3-methylphenyl)-2-[(2-methylphenyl)amino]thiophene-3-carboxamide

SMILES

Cc1cccc(NC(c2c(Nc3c(C)cccc3)sc(C(c(cc3)ccc3F)=O)c2N)=O)c1

InChI

InChI=1S/C26H22FN3O2S/c1-15-6-5-8-19(14-15)29-25(32)21-22(28)24(23(31)17-10-12-18(27)13-11-17)33-26(21)30-20-9-4-3-7-16(20)2/h3-14,30H,28H2,1-2H3,(H,29,32)

InChI Key

VUFKVLOJHZUZHV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15085711

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.992

Distribution Coefficient, logD

5.992

Water Solubility, LogSw

-5.66

Polar Surface Area

64.192

Acid Dissociation Constant (pKa)

13.67

Base Dissociation Constant (pKb)

-3.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.70

K264-0095 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Others
  • Phosphatases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with K264-0095 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K264-0095?
Check Price and Availability of K264-0095, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K264-0095 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K264-0095
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K264-0095
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K264-0095 available by request