K264-0354 Screening compound: 4-amino-2-[(5-chloro-2-methoxyphenyl)amino]-5-(4-chlorobenzoyl)thiophene-3-carbonitrile

K264-0354 Screening compound: 4-amino-2-[(5-chloro-2-methoxyphenyl)amino]-5-(4-chlorobenzoyl)thiophene-3-carbonitrile
K264-0354 Screening compound: 4-amino-2-[(5-chloro-2-methoxyphenyl)amino]-5-(4-chlorobenzoyl)thiophene-3-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound K264-0354
4-amino-2-[(5-chloro-2-methoxyphenyl)amino]-5-(4-chlorobenzoyl)thiophene-3-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K264-0354

Molecular Formula

C19H13Cl2N3O2S (C19 H13 Cl2 N3 O2 S)

Compound Name

4-amino-2-[(5-chloro-2-methoxyphenyl)amino]-5-(4-chlorobenzoyl)thiophene-3-carbonitrile

IUPAC name

4-amino-2-[(5-chloro-2-methoxyphenyl)amino]-5-(4-chlorobenzoyl)thiophene-3-carbonitrile

SMILES

COc(ccc(Cl)c1)c1Nc(sc(C(c(cc1)ccc1Cl)=O)c1N)c1C#N

InChI

InChI=1S/C19H13Cl2N3O2S/c1-26-15-7-6-12(21)8-14(15)24-19-13(9-22)16(23)18(27-19)17(25)10-2-4-11(20)5-3-10/h2-8,24H,23H2,1H3

InChI Key

UCYNATDAAIOFFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03830126

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.3

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.292

Distribution Coefficient, logD

5.292

Water Solubility, LogSw

-6.11

Polar Surface Area

65.787

Acid Dissociation Constant (pKa)

13.68

Base Dissociation Constant (pKb)

-3.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

K264-0354 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
Targets:
  • Others
Agro:
  • Agro

References: we are preparing a list of scientific research reports with K264-0354 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K264-0354?
Check Price and Availability of K264-0354, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K264-0354 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K264-0354
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K264-0354
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K264-0354 available by request