K277-0152 Screening compound: 3-[4-(2,5-dimethylphenyl)-5-ethyl-1,3-thiazol-2-yl]-2H-chromen-2-one

K277-0152 Screening compound: 3-[4-(2,5-dimethylphenyl)-5-ethyl-1,3-thiazol-2-yl]-2H-chromen-2-one
K277-0152 Screening compound: 3-[4-(2,5-dimethylphenyl)-5-ethyl-1,3-thiazol-2-yl]-2H-chromen-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K277-0152
3-[4-(2,5-dimethylphenyl)-5-ethyl-1,3-thiazol-2-yl]-2H-chromen-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K277-0152

Molecular Formula

C22H19NO2S (C22 H19 NO2 S)

Compound Name

3-[4-(2,5-dimethylphenyl)-5-ethyl-1,3-thiazol-2-yl]-2H-chromen-2-one

IUPAC name

3-[4-(25-dimethylphenyl)-5-ethyl-13-thiazol-2-yl]-2H-chromen-2-one

SMILES

CCc1c(-c2c(C)ccc(C)c2)nc(C2=Cc(cccc3)c3OC2=O)s1

InChI

InChI=1S/C22H19NO2S/c1-4-19-20(16-11-13(2)9-10-14(16)3)23-21(26-19)17-12-15-7-5-6-8-18(15)25-22(17)24/h5-12H,4H2,1-3H3

InChI Key

NPKCSDJJHPBZLW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02732169

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.220

Distribution Coefficient, logD

6.220

Water Solubility, LogSw

-5.47

Polar Surface Area

31.393

Acid Dissociation Constant (pKa)

25.20

Base Dissociation Constant (pKb)

-4.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

K277-0152 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D

References: we are preparing a list of scientific research reports with K277-0152 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K277-0152?
Check Price and Availability of K277-0152, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K277-0152 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K277-0152
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K277-0152
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K277-0152 available by request