K277-0160 Screening compound: 3-{4H,5H-naphtho[1,2-d][1,3]thiazol-2-yl}-2-oxo-2H-chromen-7-yl acetate

K277-0160 Screening compound: 3-{4H,5H-naphtho[1,2-d][1,3]thiazol-2-yl}-2-oxo-2H-chromen-7-yl acetate
K277-0160 Screening compound: 3-{4H,5H-naphtho[1,2-d][1,3]thiazol-2-yl}-2-oxo-2H-chromen-7-yl acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound K277-0160
3-{4H,5H-naphtho[1,2-d][1,3]thiazol-2-yl}-2-oxo-2H-chromen-7-yl acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K277-0160

Molecular Formula

C22H15NO4S (C22 H15 NO4 S)

Compound Name

3-{4H,5H-naphtho[1,2-d][1,3]thiazol-2-yl}-2-oxo-2H-chromen-7-yl acetate

IUPAC name

3-{4H5H-naphtho[12-d][13]thiazol-2-yl}-2-oxo-2H-chromen-7-yl acetate

SMILES

CC(Oc(cc1)cc(O2)c1C=C(c1nc(-c3c(CC4)cccc3)c4s1)C2=O)=O

InChI

InChI=1S/C22H15NO4S/c1-12(24)26-15-8-6-14-10-17(22(25)27-18(14)11-15)21-23-20-16-5-3-2-4-13(16)7-9-19(20)28-21/h2-6,8,10-11H,7,9H2,1H3

InChI Key

TZWGUTNNPMBCMM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02732993

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.609

Distribution Coefficient, logD

4.609

Water Solubility, LogSw

-4.60

Polar Surface Area

52.155

Acid Dissociation Constant (pKa)

22.67

Base Dissociation Constant (pKb)

-4.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

K277-0160 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with K277-0160 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K277-0160?
Check Price and Availability of K277-0160, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K277-0160 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K277-0160
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K277-0160
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K277-0160 available by request