K284-1961 Screening compound: N-(3-chloro-4-methylphenyl)-2-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)acetamide

K284-1961 Screening compound: N-(3-chloro-4-methylphenyl)-2-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)acetamide
K284-1961 Screening compound: N-(3-chloro-4-methylphenyl)-2-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-1961
N-(3-chloro-4-methylphenyl)-2-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-1961

Molecular Formula

C25H23ClN4O4S2 (C25 H23 ClN4 O4 S2)

Compound Name

N-(3-chloro-4-methylphenyl)-2-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)acetamide

IUPAC name

N-(3-chloro-4-methylphenyl)-2-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-34-dihydroquinazolin-2-yl}sulfanyl)acetamide

SMILES

Cc(ccc(NC(CSC(N1CCc(cc2)ccc2S(N)(=O)=O)=Nc(cccc2)c2C1=O)=O)c1)c1Cl

InChI

InChI=1S/C25H23ClN4O4S2/c1-16-6-9-18(14-21(16)26)28-23(31)15-35-25-29-22-5-3-2-4-20(22)24(32)30(25)13-12-17-7-10-19(11-8-17)36(27,33)34/h2-11,14H,12-13,15H2,1H3,(H,28,31)(H2,27,33,34)

InChI Key

YWGCBQNWVCODLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04845934

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

543.07

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.015

Distribution Coefficient, logD

4.015

Water Solubility, LogSw

-4.41

Polar Surface Area

99.502

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

0.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

K284-1961 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K284-1961 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-1961?
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What is the minimum amount of K284-1961 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-1961
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-1961
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-1961 available by request