K284-1989 Screening compound: 3-({4-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOHEXYL}METHYL)-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE

K284-1989 Screening compound: 3-({4-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOHEXYL}METHYL)-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE
K284-1989 Screening compound: 3-({4-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOHEXYL}METHYL)-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-1989
3-({4-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOHEXYL}METHYL)-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-1989

Molecular Formula

C26H30N4O2S (C26 H30 N4 O2 S)

Compound Name

3-({4-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOHEXYL}METHYL)-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE

IUPAC name

n/a

SMILES

O=C(C1CCC(CN(C(c(cccc2)c2N2)=O)C2=S)CC1)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C26H30N4O2S/c31-24(29-16-14-28(15-17-29)21-6-2-1-3-7-21)20-12-10-19(11-13-20)18-30-25(32)22-8-4-5-9-23(22)27-26(30)33/h1-9,19-20H,10-18H2,(H,27,33)

InChI Key

LOJWCKAJJWXFDG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05023677

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.62

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.763

Distribution Coefficient, logD

4.762

Water Solubility, LogSw

-4.69

Polar Surface Area

47.419

Acid Dissociation Constant (pKa)

9.99

Base Dissociation Constant (pKb)

3.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

K284-1989 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

GPCR Targeted Library (31838 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K284-1989 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-1989?
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What is the minimum amount of K284-1989 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-1989
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-1989
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-1989 available by request