K284-4344 Screening compound: 2-[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]-1-morpholino-1-butanone

K284-4344 Screening compound: 2-[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]-1-morpholino-1-butanone
K284-4344 Screening compound: 2-[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]-1-morpholino-1-butanone alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-4344
2-[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]-1-morpholino-1-butanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-4344

Molecular Formula

C22H21BrN4O2S (C22 H21 BrN4 O2 S)

Compound Name

2-[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]-1-morpholino-1-butanone

IUPAC name

2-({4-bromo-81017-triazatetracyclo[8.7.0.0^{27}.0^{1116}]heptadeca-1(17)2(7)35811(16)1214-octaen-9-yl}sulfanyl)-1-(morpholin-4-yl)butan-1-one

SMILES

CCC(C(N1CCOCC1)=O)Sc1nc(ccc(Br)c2)c2c2nc(cccc3)c3n12

InChI

InChI=1S/C22H21BrN4O2S/c1-2-19(21(28)26-9-11-29-12-10-26)30-22-25-16-8-7-14(23)13-15(16)20-24-17-5-3-4-6-18(17)27(20)22/h3-8,13,19H,2,9-12H2,1H3/t19-/m0/s1

InChI Key

MZWVNXXWMDBYSM-IBGZPJMESA-N

MDL Number (MFCD)

MFCD15088201

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.019

Distribution Coefficient, logD

5.018

Water Solubility, LogSw

-4.79

Polar Surface Area

41.647

Acid Dissociation Constant (pKa)

16.81

Base Dissociation Constant (pKb)

4.93

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

K284-4344 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K284-4344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-4344?
Check Price and Availability of K284-4344, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-4344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-4344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-4344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-4344 available by request