K284-4354 Screening compound: 2-{[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]methyl}-7-chloro-4H-pyrido[1,2-a]pyrimidin-4-one

K284-4354 Screening compound: 2-{[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]methyl}-7-chloro-4H-pyrido[1,2-a]pyrimidin-4-one
K284-4354 Screening compound: 2-{[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]methyl}-7-chloro-4H-pyrido[1,2-a]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-4354
2-{[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]methyl}-7-chloro-4H-pyrido[1,2-a]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-4354

Molecular Formula

C23H13BrClN5OS (C23 H13 BrClN5 OS)

Compound Name

2-{[(2-bromo[1,3]benzimidazo[1,2-c]quinazolin-6-yl)sulfanyl]methyl}-7-chloro-4H-pyrido[1,2-a]pyrimidin-4-one

IUPAC name

2-[({4-bromo-81017-triazatetracyclo[8.7.0.0^{27}.0^{1116}]heptadeca-1(17)2(7)35811(16)1214-octaen-9-yl}sulfanyl)methyl]-7-chloro-4H-pyrido[12-a]pyrimidin-4-one

SMILES

O=C1N(C=C(C=C2)Cl)C2=NC(CSc2nc(ccc(Br)c3)c3c3nc(cccc4)c4n23)=C1

InChI

InChI=1S/C23H13BrClN5OS/c24-13-5-7-17-16(9-13)22-27-18-3-1-2-4-19(18)30(22)23(28-17)32-12-15-10-21(31)29-11-14(25)6-8-20(29)26-15/h1-11H,12H2

InChI Key

RBTFILLRDINMCO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15088209

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

522.81

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.173

Distribution Coefficient, logD

5.172

Water Solubility, LogSw

-5.64

Polar Surface Area

43.324

Acid Dissociation Constant (pKa)

22.28

Base Dissociation Constant (pKb)

4.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

K284-4354 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K284-4354 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-4354?
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What is the minimum amount of K284-4354 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-4354
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-4354
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-4354 available by request