K284-6003 Screening compound: 2-({6,7-dimethoxy-4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)-N-(2-methoxyethyl)acetamide

K284-6003 Screening compound: 2-({6,7-dimethoxy-4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)-N-(2-methoxyethyl)acetamide
K284-6003 Screening compound: 2-({6,7-dimethoxy-4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)-N-(2-methoxyethyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-6003
2-({6,7-dimethoxy-4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)-N-(2-methoxyethyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-6003

Molecular Formula

C23H28N4O7S2 (C23 H28 N4 O7 S2)

Compound Name

2-({6,7-dimethoxy-4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)-N-(2-methoxyethyl)acetamide

IUPAC name

2-({67-dimethoxy-4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-34-dihydroquinazolin-2-yl}sulfanyl)-N-(2-methoxyethyl)acetamide

SMILES

COCCNC(CSC(N1CCc(cc2)ccc2S(N)(=O)=O)=Nc(cc(c(OC)c2)OC)c2C1=O)=O

InChI

InChI=1S/C23H28N4O7S2/c1-32-11-9-25-21(28)14-35-23-26-18-13-20(34-3)19(33-2)12-17(18)22(29)27(23)10-8-15-4-6-16(7-5-15)36(24,30)31/h4-7,12-13H,8-11,14H2,1-3H3,(H,25,28)(H2,24,30,31)

InChI Key

VYYHTTAHWADFGU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15089167

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

536.63

Hydrogen Bond Acceptors Count

14.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

13.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

0.896

Distribution Coefficient, logD

0.895

Water Solubility, LogSw

-2.42

Polar Surface Area

124.540

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

1.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

K284-6003 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Dark Chemical Matter Library (18430 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Pool
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with K284-6003 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-6003?
Check Price and Availability of K284-6003, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-6003 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-6003
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-6003
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-6003 available by request