K284-6370 Screening compound: N-[(4-chlorophenyl)methyl]-6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl]hexanamide

K284-6370 Screening compound: N-[(4-chlorophenyl)methyl]-6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl]hexanamide
K284-6370 Screening compound: N-[(4-chlorophenyl)methyl]-6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl]hexanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-6370
N-[(4-chlorophenyl)methyl]-6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl]hexanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-6370

Molecular Formula

C25H29ClN4O3S (C25 H29 ClN4 O3 S)

Compound Name

N-[(4-chlorophenyl)methyl]-6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl]hexanamide

IUPAC name

N-[(4-chlorophenyl)methyl]-6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1234-tetrahydroquinazolin-3-yl]hexanamide

SMILES

O=C(CCCCCN(C(c(cc(cc1)N2CCOCC2)c1N1)=O)C1=S)NCc(cc1)ccc1Cl

InChI

InChI=1S/C25H29ClN4O3S/c26-19-7-5-18(6-8-19)17-27-23(31)4-2-1-3-11-30-24(32)21-16-20(29-12-14-33-15-13-29)9-10-22(21)28-25(30)34/h5-10,16H,1-4,11-15,17H2,(H,27,31)(H,28,34)

InChI Key

DJJPOYVHYVGPMV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15089295

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

501.05

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.545

Distribution Coefficient, logD

3.544

Water Solubility, LogSw

-4.04

Polar Surface Area

63.129

Acid Dissociation Constant (pKa)

9.81

Base Dissociation Constant (pKb)

1.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

K284-6370 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

PI3K-Targeted Library (17255 compounds)

PLpro Library (6343 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K284-6370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-6370?
Check Price and Availability of K284-6370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-6370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-6370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-6370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-6370 available by request