K286-0141 Screening compound: 4-amino-5-(morpholine-4-carbonyl)-3-phenyl-2,3-dihydro-1,3-thiazole-2-thione

K286-0141 Screening compound: 4-amino-5-(morpholine-4-carbonyl)-3-phenyl-2,3-dihydro-1,3-thiazole-2-thione
K286-0141 Screening compound: 4-amino-5-(morpholine-4-carbonyl)-3-phenyl-2,3-dihydro-1,3-thiazole-2-thione alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0141
4-amino-5-(morpholine-4-carbonyl)-3-phenyl-2,3-dihydro-1,3-thiazole-2-thione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0141

Molecular Formula

C14H15N3O2S2 (C14 H15 N3 O2 S2)

Compound Name

4-amino-5-(morpholine-4-carbonyl)-3-phenyl-2,3-dihydro-1,3-thiazole-2-thione

IUPAC name

4-amino-5-(morpholine-4-carbonyl)-3-phenyl-23-dihydro-13-thiazole-2-thione

SMILES

NC(N1c2ccccc2)=C(C(N2CCOCC2)=O)SC1=S

InChI

InChI=1S/C14H15N3O2S2/c15-12-11(13(18)16-6-8-19-9-7-16)21-14(20)17(12)10-4-2-1-3-5-10/h1-5H,6-9,15H2

InChI Key

RDKNLTNGGDDCSS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01714128

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

321.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.239

Distribution Coefficient, logD

1.239

Water Solubility, LogSw

-2.04

Polar Surface Area

47.671

Acid Dissociation Constant (pKa)

18.18

Base Dissociation Constant (pKb)

1.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

K286-0141 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with K286-0141 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0141?
Check Price and Availability of K286-0141, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K286-0141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0141 available by request