K286-1695 Screening compound: 2-{[3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetic acid

K286-1695 Screening compound: 2-{[3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetic acid
K286-1695 Screening compound: 2-{[3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-1695
2-{[3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-1695

Molecular Formula

C20H13ClFN3O3S3 (C20 H13 ClFN3 O3 S3)

Compound Name

2-{[3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetic acid

IUPAC name

2-{[3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetic acid

SMILES

Cc(cc(cc1)N(C(N=C(N(c(cc2)ccc2F)C2=O)SCC(O)=O)=C2S2)C2=S)c1Cl

InChI

InChI=1S/C20H13ClFN3O3S3/c1-10-8-13(6-7-14(10)21)24-17-16(31-20(24)29)18(28)25(12-4-2-11(22)3-5-12)19(23-17)30-9-15(26)27/h2-8H,9H2,1H3,(H,26,27)

InChI Key

DKKTUKCVWLELRJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03030118

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.99

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.402

Distribution Coefficient, logD

1.821

Water Solubility, LogSw

-4.26

Polar Surface Area

55.610

Acid Dissociation Constant (pKa)

4.82

Base Dissociation Constant (pKb)

-9.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

K286-1695 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-1695 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-1695?
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What is the minimum amount of K286-1695 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-1695
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-1695
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-1695 available by request