K286-3237 Screening compound: 3-(2,5-dimethoxyphenyl)-6-(2-methylphenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3237 Screening compound: 3-(2,5-dimethoxyphenyl)-6-(2-methylphenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3237 Screening compound: 3-(2,5-dimethoxyphenyl)-6-(2-methylphenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3237
3-(2,5-dimethoxyphenyl)-6-(2-methylphenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3237

Molecular Formula

C21H19N3O3S3 (C21 H19 N3 O3 S3)

Compound Name

3-(2,5-dimethoxyphenyl)-6-(2-methylphenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-(25-dimethoxyphenyl)-6-(2-methylphenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

Cc(cccc1)c1N(C1=O)C(SC)=NC(N2c(cc(cc3)OC)c3OC)=C1SC2=S

InChI

InChI=1S/C21H19N3O3S3/c1-12-7-5-6-8-14(12)24-19(25)17-18(22-20(24)29-4)23(21(28)30-17)15-11-13(26-2)9-10-16(15)27-3/h5-11H,1-4H3

InChI Key

YJFMYWYCTWTZDQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090477

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.6

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.603

Distribution Coefficient, logD

4.603

Water Solubility, LogSw

-4.46

Polar Surface Area

41.798

Acid Dissociation Constant (pKa)

28.80

Base Dissociation Constant (pKb)

-9.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

K286-3237 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3237 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3237?
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What is the minimum amount of K286-3237 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3237
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3237
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3237 available by request