K286-3354 Screening compound: 3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-2,5-disulfanylidene-2H,3H,4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3354 Screening compound: 3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-2,5-disulfanylidene-2H,3H,4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3354 Screening compound: 3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-2,5-disulfanylidene-2H,3H,4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3354
3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-2,5-disulfanylidene-2H,3H,4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3354

Molecular Formula

C18H11ClFN3OS3 (C18 H11 ClFN3 OS3)

Compound Name

3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-2,5-disulfanylidene-2H,3H,4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-(4-chloro-3-methylphenyl)-6-(4-fluorophenyl)-25-disulfanylidene-2H3H4H5H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

Cc(cc(cc1)N(C(NC(N(c(cc2)ccc2F)C2=O)=S)=C2S2)C2=S)c1Cl

InChI

InChI=1S/C18H11ClFN3OS3/c1-9-8-12(6-7-13(9)19)22-15-14(27-18(22)26)16(24)23(17(25)21-15)11-4-2-10(20)3-5-11/h2-8H,1H3,(H,21,25)

InChI Key

FQPIVQFVFWJZLN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090520

Chemical and Physical Properties

Saltdata

(C2H5)3N

Molecular Weight

435.95

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.957

Distribution Coefficient, logD

4.957

Water Solubility, LogSw

-5.11

Polar Surface Area

28.501

Acid Dissociation Constant (pKa)

12.52

Base Dissociation Constant (pKb)

-1.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

K286-3354 in Drug Discovery

Included in Screening Libraries

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with K286-3354 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3354?
Check Price and Availability of K286-3354, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K286-3354 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3354
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3354
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3354 available by request