K286-3551 Screening compound: 4-amino-3-(4-chloro-3-methylphenyl)-N-(4-methylphenyl)-2-sulfanylidene-2,3-dihydro-1,3-thiazole-5-carboxamide

K286-3551 Screening compound: 4-amino-3-(4-chloro-3-methylphenyl)-N-(4-methylphenyl)-2-sulfanylidene-2,3-dihydro-1,3-thiazole-5-carboxamide
K286-3551 Screening compound: 4-amino-3-(4-chloro-3-methylphenyl)-N-(4-methylphenyl)-2-sulfanylidene-2,3-dihydro-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3551
4-amino-3-(4-chloro-3-methylphenyl)-N-(4-methylphenyl)-2-sulfanylidene-2,3-dihydro-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3551

Molecular Formula

C18H16ClN3OS2 (C18 H16 ClN3 OS2)

Compound Name

4-amino-3-(4-chloro-3-methylphenyl)-N-(4-methylphenyl)-2-sulfanylidene-2,3-dihydro-1,3-thiazole-5-carboxamide

IUPAC name

4-amino-3-(4-chloro-3-methylphenyl)-N-(4-methylphenyl)-2-sulfanylidene-23-dihydro-13-thiazole-5-carboxamide

SMILES

Cc(cc1)ccc1NC(C(SC1=S)=C(N)N1c(cc1)cc(C)c1Cl)=O

InChI

InChI=1S/C18H16ClN3OS2/c1-10-3-5-12(6-4-10)21-17(23)15-16(20)22(18(24)25-15)13-7-8-14(19)11(2)9-13/h3-9H,20H2,1-2H3,(H,21,23)

InChI Key

VNEXPSDTISBVPU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06742953

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.93

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.980

Distribution Coefficient, logD

4.980

Water Solubility, LogSw

-5.07

Polar Surface Area

46.206

Acid Dissociation Constant (pKa)

14.03

Base Dissociation Constant (pKb)

1.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

K286-3551 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with K286-3551 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3551?
Check Price and Availability of K286-3551, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K286-3551 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3551
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3551
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3551 available by request