K286-3650 Screening compound: 6-cyclohexyl-5-{[(2-fluorophenyl)methyl]sulfanyl}-3-(2-phenylethyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3650 Screening compound: 6-cyclohexyl-5-{[(2-fluorophenyl)methyl]sulfanyl}-3-(2-phenylethyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3650 Screening compound: 6-cyclohexyl-5-{[(2-fluorophenyl)methyl]sulfanyl}-3-(2-phenylethyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3650
6-cyclohexyl-5-{[(2-fluorophenyl)methyl]sulfanyl}-3-(2-phenylethyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3650

Molecular Formula

C26H26FN3OS3 (C26 H26 FN3 OS3)

Compound Name

6-cyclohexyl-5-{[(2-fluorophenyl)methyl]sulfanyl}-3-(2-phenylethyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

6-cyclohexyl-5-{[(2-fluorophenyl)methyl]sulfanyl}-3-(2-phenylethyl)-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

O=C1N(C2CCCCC2)C(SCc(cccc2)c2F)=NC(N2CCc3ccccc3)=C1SC2=S

InChI

InChI=1S/C26H26FN3OS3/c27-21-14-8-7-11-19(21)17-33-25-28-23-22(24(31)30(25)20-12-5-2-6-13-20)34-26(32)29(23)16-15-18-9-3-1-4-10-18/h1,3-4,7-11,14,20H,2,5-6,12-13,15-17H2

InChI Key

FWYGYHIAXHOWTF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090638

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

511.71

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.879

Distribution Coefficient, logD

6.879

Water Solubility, LogSw

-5.92

Polar Surface Area

27.377

Acid Dissociation Constant (pKa)

26.44

Base Dissociation Constant (pKb)

-0.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

K286-3650 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K286-3650 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3650?
Check Price and Availability of K286-3650, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K286-3650 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3650
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3650
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3650 available by request