K286-4072 Screening compound: 3-(3,4-dimethylphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-4072 Screening compound: 3-(3,4-dimethylphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-4072 Screening compound: 3-(3,4-dimethylphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-4072
3-(3,4-dimethylphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-4072

Molecular Formula

C27H23N3OS3 (C27 H23 N3 OS3)

Compound Name

3-(3,4-dimethylphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-(34-dimethylphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

Cc(cc1)c(C)cc1N(C(N=C(N(c1ccccc1)C1=O)SCc2c(C)cccc2)=C1S1)C1=S

InChI

InChI=1S/C27H23N3OS3/c1-17-13-14-22(15-19(17)3)29-24-23(34-27(29)32)25(31)30(21-11-5-4-6-12-21)26(28-24)33-16-20-10-8-7-9-18(20)2/h4-15H,16H2,1-3H3

InChI Key

GABFJUONNSPTHY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090933

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

501.7

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.321

Distribution Coefficient, logD

7.321

Water Solubility, LogSw

-5.57

Polar Surface Area

26.954

Acid Dissociation Constant (pKa)

28.43

Base Dissociation Constant (pKb)

1.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

K286-4072 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-4072 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-4072?
Check Price and Availability of K286-4072, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K286-4072 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-4072
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-4072
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-4072 available by request