K286-4262 Screening compound: methyl 2-(2-{[6-(4-fluorophenyl)-3-[(furan-2-yl)methyl]-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamido)benzoate

K286-4262 Screening compound: methyl 2-(2-{[6-(4-fluorophenyl)-3-[(furan-2-yl)methyl]-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamido)benzoate
K286-4262 Screening compound: methyl 2-(2-{[6-(4-fluorophenyl)-3-[(furan-2-yl)methyl]-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-4262
methyl 2-(2-{[6-(4-fluorophenyl)-3-[(furan-2-yl)methyl]-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-4262

Molecular Formula

C26H19FN4O5S3 (C26 H19 FN4 O5 S3)

Compound Name

methyl 2-(2-{[6-(4-fluorophenyl)-3-[(furan-2-yl)methyl]-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamido)benzoate

IUPAC name

methyl 2-(2-{[6-(4-fluorophenyl)-3-[(furan-2-yl)methyl]-7-oxo-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetamido)benzoate

SMILES

COC(c(cccc1)c1NC(CSC(N(c(cc1)ccc1F)C1=O)=NC(N2Cc3ccco3)=C1SC2=S)=O)=O

InChI

InChI=1S/C26H19FN4O5S3/c1-35-24(34)18-6-2-3-7-19(18)28-20(32)14-38-25-29-22-21(23(33)31(25)16-10-8-15(27)9-11-16)39-26(37)30(22)13-17-5-4-12-36-17/h2-12H,13-14H2,1H3,(H,28,32)

InChI Key

YUACAWLYYHKNPP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091063

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

582.66

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.390

Distribution Coefficient, logD

4.384

Water Solubility, LogSw

-4.40

Polar Surface Area

78.940

Acid Dissociation Constant (pKa)

9.21

Base Dissociation Constant (pKb)

0.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

K286-4262 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-4262 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-4262?
Check Price and Availability of K286-4262, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K286-4262 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-4262
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-4262
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-4262 available by request