K286-4292 Screening compound: 5-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-4292 Screening compound: 5-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-4292 Screening compound: 5-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-4292
5-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-4292

Molecular Formula

C24H16ClN3O3S3 (C24 H16 ClN3 O3 S3)

Compound Name

5-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

5-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

O=C(CSC(N(c1ccccc1)C1=O)=NC(N2Cc3ccco3)=C1SC2=S)c(cc1)ccc1Cl

InChI

InChI=1S/C24H16ClN3O3S3/c25-16-10-8-15(9-11-16)19(29)14-33-23-26-21-20(22(30)28(23)17-5-2-1-3-6-17)34-24(32)27(21)13-18-7-4-12-31-18/h1-12H,13-14H2

InChI Key

ODWZBQLTENXAMX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091087

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

526.06

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.237

Distribution Coefficient, logD

5.237

Water Solubility, LogSw

-5.84

Polar Surface Area

48.562

Acid Dissociation Constant (pKa)

26.88

Base Dissociation Constant (pKb)

1.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

K286-4292 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-4292 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-4292?
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What is the minimum amount of K286-4292 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-4292
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-4292
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-4292 available by request