K288-0476 Screening compound: N-[3-(morpholin-4-yl)propyl]-4-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl)benzamide

K288-0476 Screening compound: N-[3-(morpholin-4-yl)propyl]-4-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl)benzamide
K288-0476 Screening compound: N-[3-(morpholin-4-yl)propyl]-4-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K288-0476
N-[3-(morpholin-4-yl)propyl]-4-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K288-0476

Molecular Formula

C22H24N4O3S (C22 H24 N4 O3 S)

Compound Name

N-[3-(morpholin-4-yl)propyl]-4-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl)benzamide

IUPAC name

N-[3-(morpholin-4-yl)propyl]-4-(4-oxo-2-sulfanylidene-1234-tetrahydroquinazolin-3-yl)benzamide

SMILES

O=C(c(cc1)ccc1N(C(c(cccc1)c1N1)=O)C1=S)NCCCN1CCOCC1

InChI

InChI=1S/C22H24N4O3S/c27-20(23-10-3-11-25-12-14-29-15-13-25)16-6-8-17(9-7-16)26-21(28)18-4-1-2-5-19(18)24-22(26)30/h1-2,4-9H,3,10-15H2,(H,23,27)(H,24,30)

InChI Key

FMFTVLYCARDBKC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02651669

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.560

Distribution Coefficient, logD

1.172

Water Solubility, LogSw

-2.51

Polar Surface Area

62.852

Acid Dissociation Constant (pKa)

9.27

Base Dissociation Constant (pKb)

7.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

K288-0476 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K288-0476 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K288-0476?
Check Price and Availability of K288-0476, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K288-0476 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K288-0476
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K288-0476
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K288-0476 available by request