K292-1172 Screening compound: 6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-(2-phenylethyl)hexanamide

K292-1172 Screening compound: 6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-(2-phenylethyl)hexanamide
K292-1172 Screening compound: 6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-(2-phenylethyl)hexanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K292-1172
6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-(2-phenylethyl)hexanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K292-1172

Molecular Formula

C29H28ClN5O3S2 (C29 H28 ClN5 O3 S2)

Compound Name

6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-(2-phenylethyl)hexanamide

IUPAC name

6-{2-[({7-chloro-4-oxo-4H-pyrido[12-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H4H-thieno[32-d]pyrimidin-3-yl}-N-(2-phenylethyl)hexanamide

SMILES

O=C(CCCCCN(C1=O)C(SCC(N=C(C=C2)N3C=C2Cl)=CC3=O)=Nc2c1scc2)NCCc1ccccc1

InChI

InChI=1S/C29H28ClN5O3S2/c30-21-10-11-24-32-22(17-26(37)35(24)18-21)19-40-29-33-23-13-16-39-27(23)28(38)34(29)15-6-2-5-9-25(36)31-14-12-20-7-3-1-4-8-20/h1,3-4,7-8,10-11,13,16-18H,2,5-6,9,12,14-15,19H2,(H,31,36)

InChI Key

XXHZOJXTGWONAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091679

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

594.16

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

13.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.352

Distribution Coefficient, logD

3.352

Water Solubility, LogSw

-3.76

Polar Surface Area

77.586

Acid Dissociation Constant (pKa)

14.38

Base Dissociation Constant (pKb)

1.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.60

K292-1172 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with K292-1172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K292-1172?
Check Price and Availability of K292-1172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K292-1172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K292-1172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K292-1172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K292-1172 available by request