K292-1350 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(butan-2-yl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide

K292-1350 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(butan-2-yl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide
K292-1350 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(butan-2-yl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K292-1350
N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(butan-2-yl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K292-1350

Molecular Formula

C24H28N4O5S2 (C24 H28 N4 O5 S2)

Compound Name

N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(butan-2-yl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide

IUPAC name

N-[(2H-13-benzodioxol-5-yl)methyl]-4-[2-({[(butan-2-yl)carbamoyl]methyl}sulfanyl)-4-oxo-3H4H-thieno[32-d]pyrimidin-3-yl]butanamide

SMILES

CCC(C)NC(CSC(N(CCCC(NCc(cc1)cc2c1OCO2)=O)C1=O)=Nc2c1scc2)=O

InChI

InChI=1S/C24H28N4O5S2/c1-3-15(2)26-21(30)13-35-24-27-17-8-10-34-22(17)23(31)28(24)9-4-5-20(29)25-12-16-6-7-18-19(11-16)33-14-32-18/h6-8,10-11,15H,3-5,9,12-14H2,1-2H3,(H,25,29)(H,26,30)/t15-/m0/s1

InChI Key

CLQQEOPJAQLECO-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD15091819

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

516.64

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

13.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.336

Distribution Coefficient, logD

2.336

Water Solubility, LogSw

-2.85

Polar Surface Area

92.539

Acid Dissociation Constant (pKa)

14.52

Base Dissociation Constant (pKb)

6.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.70

K292-1350 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K292-1350 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K292-1350?
Check Price and Availability of K292-1350, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K292-1350 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K292-1350
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K292-1350
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K292-1350 available by request