K292-1371 Screening compound: 6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-[2-(3,4-dimethoxyphenyl)ethyl]hexanamide

K292-1371 Screening compound: 6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-[2-(3,4-dimethoxyphenyl)ethyl]hexanamide
K292-1371 Screening compound: 6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-[2-(3,4-dimethoxyphenyl)ethyl]hexanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K292-1371
6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-[2-(3,4-dimethoxyphenyl)ethyl]hexanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K292-1371

Molecular Formula

C31H32ClN5O5S2 (C31 H32 ClN5 O5 S2)

Compound Name

6-{2-[({7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}-N-[2-(3,4-dimethoxyphenyl)ethyl]hexanamide

IUPAC name

6-{2-[({7-chloro-4-oxo-4H-pyrido[12-a]pyrimidin-2-yl}methyl)sulfanyl]-4-oxo-3H4H-thieno[32-d]pyrimidin-3-yl}-N-[2-(34-dimethoxyphenyl)ethyl]hexanamide

SMILES

COc(ccc(CCNC(CCCCCN(C1=O)C(SCC(N=C(C=C2)N3C=C2Cl)=CC3=O)=Nc2c1scc2)=O)c1)c1OC

InChI

InChI=1S/C31H32ClN5O5S2/c1-41-24-9-7-20(16-25(24)42-2)11-13-33-27(38)6-4-3-5-14-36-30(40)29-23(12-15-43-29)35-31(36)44-19-22-17-28(39)37-18-21(32)8-10-26(37)34-22/h7-10,12,15-18H,3-6,11,13-14,19H2,1-2H3,(H,33,38)

InChI Key

KWVLYKNJDPKQHC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091837

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

654.21

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

15.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.870

Distribution Coefficient, logD

2.870

Water Solubility, LogSw

-3.62

Polar Surface Area

92.847

Acid Dissociation Constant (pKa)

14.38

Base Dissociation Constant (pKb)

1.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.30

K292-1371 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with K292-1371 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K292-1371?
Check Price and Availability of K292-1371, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K292-1371 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K292-1371
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K292-1371
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K292-1371 available by request