K292-1504 Screening compound: 5-{4-oxo-2-[({[2-(trifluoromethyl)phenyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}pentanoic acid

K292-1504 Screening compound: 5-{4-oxo-2-[({[2-(trifluoromethyl)phenyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}pentanoic acid
K292-1504 Screening compound: 5-{4-oxo-2-[({[2-(trifluoromethyl)phenyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}pentanoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K292-1504
5-{4-oxo-2-[({[2-(trifluoromethyl)phenyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}pentanoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K292-1504

Molecular Formula

C20H18F3N3O4S2 (C20 H18 F3 N3 O4 S2)

Compound Name

5-{4-oxo-2-[({[2-(trifluoromethyl)phenyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}pentanoic acid

IUPAC name

5-{4-oxo-2-[({[2-(trifluoromethyl)phenyl]carbamoyl}methyl)sulfanyl]-3H4H-thieno[32-d]pyrimidin-3-yl}pentanoic acid

SMILES

OC(CCCCN(C1=O)C(SCC(Nc2c(C(F)(F)F)cccc2)=O)=Nc2c1scc2)=O

InChI

InChI=1S/C20H18F3N3O4S2/c21-20(22,23)12-5-1-2-6-13(12)24-15(27)11-32-19-25-14-8-10-31-17(14)18(30)26(19)9-4-3-7-16(28)29/h1-2,5-6,8,10H,3-4,7,9,11H2,(H,24,27)(H,28,29)

InChI Key

NTSZTBZYYBENLV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091900

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.020

Distribution Coefficient, logD

0.192

Water Solubility, LogSw

-3.63

Polar Surface Area

77.875

Acid Dissociation Constant (pKa)

4.57

Base Dissociation Constant (pKb)

-1.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

K292-1504 in Drug Discovery

Included in Screening Libraries

Human Proteases Annotated Library (2868 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with K292-1504 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K292-1504?
Check Price and Availability of K292-1504, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K292-1504 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K292-1504
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K292-1504
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K292-1504 available by request