K292-1664 Screening compound: 4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxylic acid

K292-1664 Screening compound: 4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxylic acid
K292-1664 Screening compound: 4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K292-1664
4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K292-1664

Molecular Formula

C24H28N4O6S3 (C24 H28 N4 O6 S3)

Compound Name

4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxylic acid

IUPAC name

4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H4H-thieno[32-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxylic acid

SMILES

NS(c1ccc(CCNC(CSC(N(CC(CC2)CCC2C(O)=O)C2=O)=Nc3c2scc3)=O)cc1)(=O)=O

InChI

InChI=1S/C24H28N4O6S3/c25-37(33,34)18-7-3-15(4-8-18)9-11-26-20(29)14-36-24-27-19-10-12-35-21(19)22(30)28(24)13-16-1-5-17(6-2-16)23(31)32/h3-4,7-8,10,12,16-17H,1-2,5-6,9,11,13-14H2,(H,26,29)(H,31,32)(H2,25,33,34)

InChI Key

GJVOLYVEJKDBDM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091981

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

564.71

Hydrogen Bond Acceptors Count

14.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.445

Distribution Coefficient, logD

-1.115

Water Solubility, LogSw

-2.17

Polar Surface Area

130.306

Acid Dissociation Constant (pKa)

4.84

Base Dissociation Constant (pKb)

-0.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

K292-1664 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Epigenetic
Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system

References: we are preparing a list of scientific research reports with K292-1664 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K292-1664?
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What is the minimum amount of K292-1664 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K292-1664
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K292-1664
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K292-1664 available by request