K292-1888 Screening compound: 4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)benzoic acid

K292-1888 Screening compound: 4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)benzoic acid
K292-1888 Screening compound: 4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)benzoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K292-1888
4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)benzoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K292-1888

Molecular Formula

C24H22N4O6S3 (C24 H22 N4 O6 S3)

Compound Name

4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)benzoic acid

IUPAC name

4-({4-oxo-2-[({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)sulfanyl]-3H4H-thieno[32-d]pyrimidin-3-yl}methyl)benzoic acid

SMILES

NS(c1ccc(CCNC(CSC(N(Cc(cc2)ccc2C(O)=O)C2=O)=Nc3c2scc3)=O)cc1)(=O)=O

InChI

InChI=1S/C24H22N4O6S3/c25-37(33,34)18-7-3-15(4-8-18)9-11-26-20(29)14-36-24-27-19-10-12-35-21(19)22(30)28(24)13-16-1-5-17(6-2-16)23(31)32/h1-8,10,12H,9,11,13-14H2,(H,26,29)(H,31,32)(H2,25,33,34)

InChI Key

IRXZYTJMFHJEAX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15092094

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

558.66

Hydrogen Bond Acceptors Count

14.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.052

Distribution Coefficient, logD

-0.920

Water Solubility, LogSw

-2.68

Polar Surface Area

130.114

Acid Dissociation Constant (pKa)

4.43

Base Dissociation Constant (pKb)

-0.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

K292-1888 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K292-1888 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K292-1888?
Check Price and Availability of K292-1888, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K292-1888 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K292-1888
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K292-1888
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K292-1888 available by request