K297-0143 Screening compound: 2-[(4-{[(4-chlorophenyl)methyl]amino}quinazolin-2-yl)sulfanyl]-N-(4-ethoxyphenyl)acetamide

K297-0143 Screening compound: 2-[(4-{[(4-chlorophenyl)methyl]amino}quinazolin-2-yl)sulfanyl]-N-(4-ethoxyphenyl)acetamide
K297-0143 Screening compound: 2-[(4-{[(4-chlorophenyl)methyl]amino}quinazolin-2-yl)sulfanyl]-N-(4-ethoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K297-0143
2-[(4-{[(4-chlorophenyl)methyl]amino}quinazolin-2-yl)sulfanyl]-N-(4-ethoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K297-0143

Molecular Formula

C25H23ClN4O2S (C25 H23 ClN4 O2 S)

Compound Name

2-[(4-{[(4-chlorophenyl)methyl]amino}quinazolin-2-yl)sulfanyl]-N-(4-ethoxyphenyl)acetamide

IUPAC name

2-[(4-{[(4-chlorophenyl)methyl]amino}quinazolin-2-yl)sulfanyl]-N-(4-ethoxyphenyl)acetamide

SMILES

CCOc(cc1)ccc1NC(CSc1nc2ccccc2c(NCc(cc2)ccc2Cl)n1)=O

InChI

InChI=1S/C25H23ClN4O2S/c1-2-32-20-13-11-19(12-14-20)28-23(31)16-33-25-29-22-6-4-3-5-21(22)24(30-25)27-15-17-7-9-18(26)10-8-17/h3-14H,2,15-16H2,1H3,(H,28,31)(H,27,29,30)

InChI Key

FCIBTXQMMQLKEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15092281

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.962

Distribution Coefficient, logD

5.962

Water Solubility, LogSw

-6.05

Polar Surface Area

58.122

Acid Dissociation Constant (pKa)

12.50

Base Dissociation Constant (pKb)

3.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

K297-0143 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with K297-0143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K297-0143?
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What is the minimum amount of K297-0143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K297-0143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K297-0143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K297-0143 available by request