K306-0270 Screening compound: 2-chloro-6-[4-(2,5-dimethylphenyl)piperazine-1-carbonyl]-11H-pyrido[2,1-b]quinazolin-11-one

K306-0270 Screening compound: 2-chloro-6-[4-(2,5-dimethylphenyl)piperazine-1-carbonyl]-11H-pyrido[2,1-b]quinazolin-11-one
K306-0270 Screening compound: 2-chloro-6-[4-(2,5-dimethylphenyl)piperazine-1-carbonyl]-11H-pyrido[2,1-b]quinazolin-11-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K306-0270
2-chloro-6-[4-(2,5-dimethylphenyl)piperazine-1-carbonyl]-11H-pyrido[2,1-b]quinazolin-11-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K306-0270

Molecular Formula

C25H23ClN4O2 (C25 H23 ClN4 O2)

Compound Name

2-chloro-6-[4-(2,5-dimethylphenyl)piperazine-1-carbonyl]-11H-pyrido[2,1-b]quinazolin-11-one

IUPAC name

2-chloro-6-[4-(25-dimethylphenyl)piperazine-1-carbonyl]-11H-pyrido[21-b]quinazolin-11-one

SMILES

Cc1cc(N(CC2)CCN2C(C(C2=Nc(cc3)c4cc3Cl)=CC=CN2C4=O)=O)c(C)cc1

InChI

InChI=1S/C25H23ClN4O2/c1-16-5-6-17(2)22(14-16)28-10-12-29(13-11-28)24(31)19-4-3-9-30-23(19)27-21-8-7-18(26)15-20(21)25(30)32/h3-9,14-15H,10-13H2,1-2H3

InChI Key

UXILQMALWNUMHS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15093097

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.94

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.219

Distribution Coefficient, logD

4.219

Water Solubility, LogSw

-4.50

Polar Surface Area

44.113

Acid Dissociation Constant (pKa)

28.55

Base Dissociation Constant (pKb)

2.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

K306-0270 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with K306-0270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K306-0270?
Check Price and Availability of K306-0270, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K306-0270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K306-0270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K306-0270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K306-0270 available by request